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Advances in protein molecular and structural biology methods  Cover Image Book Book

Advances in protein molecular and structural biology methods / edited by Timir Tripathi, Vikash Kumar Dubey.

Tripathi, Timir (editor.). Dubey, Vikash Kumar (editor.).

Summary:

Advances in Protein Molecular and Structural Biology Methods offers a complete overview of the latest tools and methods applicable to the study of proteins at the molecular and structural level. The book begins with sections exploring tools to optimize recombinant protein expression and biophysical techniques such as fluorescence spectroscopy, NMR, mass spectrometry, cryo-electron microscopy, and X-ray crystallography. It then moves towards computational approaches, considering structural bioinformatics, molecular dynamics simulations, and deep machine learning technologies. The book also covers methods applied to intrinsically disordered proteins (IDPs)followed by chapters on protein interaction networks, protein function, and protein design and engineering. It provides researchers with an extensive toolkit of methods and techniques to draw from when conducting their own experimental work, taking them from foundational concepts to practical application.

Record details

  • ISBN: 9780323902649 (softcover)
  • Physical Description: xxvii, 685 pages : illustrations ; 28 cm
  • Publisher: London : Academic Press, [2022]

Content descriptions

Bibliography, etc. Note:
Includes bibliographical references and index.
Formatted Contents Note:
Strategies to improve the expression and solubility of recombinant proteins in E. coli -- Advances in heterologous protein expression strategies in yeast and insect systems -- Methods for transient expression and purification of monoclonal antibodies in mammalian cells -- Methods for recombinant production and purification of intrinsically disordered proteins -- Methods to determine the oligomeric structure of proteins -- Multimodal methods to study protein aggregation and fibrillation -- Experimental methods to study the thermodynamics of protein-protein interactions -- Experimental methods to study the kinetics of protein-protein interactions -- Computational techniques for studying protein-protein interactions -- Experimental methods to study protein-nucleic acid interactions -- Advanced computational tools for quantitative anaylsis of protein-nucleic acid interfaces -- Experimental techniques to study protein dynamics and conformations -- Computational techniques to study protein dynamics and conformations -- Application of circular dichroism spectroscopy in studying protein folding, stability, and interaction -- Studying protein-folding dynamics using single-molecule fluorescence methods -- Advances in liquid-state NMR spectroscopy to study the structure, function, and dynamics of biomacromolecules -- In-cell NMR spectroscopy : a tool to study cellular structure biology -- Current trends in membrance protein crystallography -- Advances in sample preparation and data processing for single-particle cryo-electron microscopy -- Advanced mass spectrometry-based methods for protein molecular-structural biologists --
Developments, advancements, and contributions of mass spectrometry in omics technologies -- Role of structural biology methods in drug discovery -- Prediction, validation, and analysis of protein structures : a beginner's guide -- Advances in structure-based virtual screening for drug discovery -- Methods and applications of machine learning in structure-based drug discovery -- Molecular dynamics simulations : principles, methods, and applications in protein conformational dynamics -- Applications of molecular dynamics simulations in drug discovery -- Envisaging the conformational space of proteins by coupling machine learning and molecular dynamics -- Immunoinformatics and reverse vaccinology methods to design peptide-based vaccines -- Computational methods to study intrinsically disordered proteins -- Experimental methods to study intrinsically disordered proteins -- Analysis of structure and dynamics of intrinsically disordered regions in proteins using solution NMR methods -- Methods to study the effect of solution variables on the conformational dynamics of intrinsically disordered proteins -- Molecular simulations to study IDP-IDP interactions and their complexes -- Exploring large-scale protein function using systematic mutant analysis -- Approaches and methods to study cell signaling -- linguistics of cellular communication -- Methods to study systems biology of signaling networks : a case study of NSCLC -- Advancements in the analysis of protein post-translational modifications -- Protein engineering : methods and applications -- Designer 3D-DNA nanodevices : structures, functions, and cellular applications.
Subject: Proteins > Structure.
Molecular biology.

Available copies

  • 1 of 1 copy available at University College of the North Libraries.

Holds

  • 0 current holds with 1 total copy.
Show Only Available Copies
Location Call Number / Copy Notes Barcode Shelving Location Holdable? Status Due Date
The Pas Campus Library QP 551 .A383 2022 (Text) 58500000809087 Stacks Volume hold Available -


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