Organic chemistry with biological applications

Summary: "Renowned for its student-friendly writing style and fresh perspective, John McMurry's ORGANIC CHEMISTRY WITH BIOLOGICAL APPLICATIONS provides full coverage of the foundations of organic chemistry -- enhanced by biological examples throughout. In addition, McMurry discusses the organic chemistry behind biological pathways. The third edition is updated with new problems, illustrations, and essays. Available digital options include the MindTap® Reader and OWLv2, the leading online homework and learning system for chemistry."--Publisher's website.

Record details

ISBN: 9781285867847
ISBN: 128586784X
ISBN: 128584291X
ISBN: 9781285842912
Physical Description: 1 volume (various pagings) : color illustrations ; 25 cm
print
Edition: 3rd Edition.
Publisher: Stamford, CT : Cengage Learning, [2015]
Copyright: ©2015

Content descriptions

General Note:

Includes index.

Formatted Contents Note:

Contents note continued: 15-3. Biological Acids and the Henderson-Hasselbalch Equation -- 15-4. Substituent Effects on Acidity -- 15-5. Preparing Carboxylic Acids -- 15-6. Reactions of Carboxylic Acids: An Overview -- 15-7. Chemistry of Nitriles -- 15-8. Spectroscopy of Carboxylic Acids and Nitriles -- Something Extra Vitamin C -- 16. Carboxylic Acid Derivatives: Nucleophilic Acyl Substitution Reactions -- 16-1. Naming Carboxylic Acid Derivatives -- 16-2. Nucleophilic Acyl Substitution Reactions -- 16-3. Reactions of Carboxylic Acids -- 16-4. Reactions of Acid Halides -- 16-5. Reactions of Acid Anhydrides -- 16-6. Reactions of Esters -- 16-7. Reactions of Amides -- 16-8. Reactions ofThioesters and Acyl Phosphates: Biological Carboxylic Acid Derivatives -- 16-9. Polyamides and Polyesters: Step-Growth Polymers -- 16-10. Spectroscopy of Carboxylic Acid Derivatives -- Something Extra Lactam Antibiotics -- 17. Carbonyl Alpha-Substitution and Condensation Reactions -- 17-1. Keto-Enol Tautomerism -- 17-2. Reactivity of Enols: a-Substitution Reactions -- 17-3. Alpha Bromination of Carboxylic Acids -- 17-4. Acidity of a Hydrogen Atoms: Enolate Ion Formation -- 17-5. Alkylation of Enolate Ions -- 17-6. Carbonyl Condensations: The Aldol Reaction -- 17-7. Dehydration of Aldol Products -- 17-8. Intramolecular Aldol Reactions -- 17-9. Claisen Condensation Reaction -- 17-10. Intramolecular Claisen Condensations: The Dieckmann Cyclization -- 17-11. Conjugate Carbonyl Additions: The Michael Reaction -- 17-12. Carbonyl Condensations with Enamines: The Stork Reaction -- 17-13. Biological Carbonyl Condensation Reactions -- Something Extra Barbiturates -- 18. Amines and Heterocycles -- 18-1. Naming Amines -- 18-2. Properties of Amines -- 18-3. Basicity of Amines -- 18-4. Basicity of Arylamines -- 18-5. Biological Amines and the Henderson-Hasselbalch Equation -- 18-6. Synthesis of Amines -- 18-7. Reactions of Amines -- 18-8. Heterocyclic Amines -- 18-9. Fused-Ring Heterocycles -- 18-10. Spectroscopy of Amines -- Something Extra Green Chemistry -- 19. Biomolecules: Amino Acids. Peptides, and Proteins -- 19-1. Structures of Amino Acids -- 19-2. Amino Acids and the Henderson-Hasselbalch Equation: Isoelectric Points -- 19-3. Synthesis of Amino Acids -- 19-4. Peptides and Proteins -- 19-5. Amino Acid Analysis of Peptides -- 19-6. Peptide Sequencing: The Edman Degradation -- 19-7. Peptide Synthesis -- 19-8. Protein Structure -- 19-9. Enzymes and Coenzymes -- 19-10. How Do Enzymes Work? Citrate Synthase -- Something Extra The Protein Data Bank -- 20. Amino Acid Metabolism -- 20-1. Overview of Metabolism and Biochemical Energy -- 20-2. Catabolism of Amino Acids: Deamination -- 20-3. Urea Cycle -- 20-4. Catabolism of Amino Acids: The Carbon Chains -- 20-5. Biosynthesis of Amino Acids -- Something Extra Visualizing Enzyme Structures -- 21. Biomolecules: Carbohydrates -- 21-1. Classifying Carbohydrates -- 21-2. Representing Carbohydrate Stereochemistry: Fischer Projections -- 21-3. D, L Sugars -- 21-4. Configurations of the Aldoses -- 21-5. Cyclic Structures of Monosaccharides: Anomers -- 21-6. Reactions of Monosaccharides -- 21-7. Eight Essential Monosaccharides -- 21-8. Disaccharides -- 21-9. Polysaccharides and Their Synthesis -- 21-10. Some Other Important Carbohydrates -- Something Extra Sweetness -- 22. Carbohydrate Metabolism -- 22-1. Hydrolysis of Complex Carbohydrates -- 22-2. Catabolism of Glucose: Glycolysis -- 22-3. Conversion of Pyruvate to Acetyl CoA -- 22-4. Citric Acid Cycle -- 22-5. Biosynthesis of Glucose: Gluconeogenesis -- Something Extra Influenza Pandemics -- 23. Biomolecules: Lipids and Their Metabolism -- 23-1. Waxes, Fats, and Oils -- 23-2. Soap -- 23-3. Phospholipids -- 23-4. Catabolism of Triacylglycerols: The Fate of Glycerol -- 23-5. Catabolism of Triacylglycerols: β-Oxidation -- 23-6. Biosynthesis of Fatty Acids -- 23-7. Prostaglandins and Other Eicosanoids -- 23-8. Terpenoids -- 23-9. Steroids -- 23-10. Biosynthesis of Steroids -- 23-11. Some Final Comments on Metabolism -- Something Extra Statin Drugs -- 24. Biomolecules: Nucleic Acids and Their Metabolism j -- 24-1. Nucleotides and Nucleic Acids -- 24-2. Base Pairing in DNA: The Watson-Crick Model -- 24-3. Replication of DNA -- 24-4. Transcription of DNA -- 24-5. Translation of RNA: Protein Biosynthesis -- 24-6. DNA Sequencing -- 24-7. DNA Synthesis -- 24-8. Polymerase Chain Reaction -- 24-9. Catabolism of Nucleotides -- 24-10. Biosynthesis of Nucleotides -- Something Extra DNA Fingerprinting -- e25. Secondary Metabolites: An Introduction to Natural Products Chemistry -- 25-1. Classifying Natural Products -- 25-2. Biosynthesis of Pyridoxal Phosphate -- 25-3. Biosynthesis of Morphine -- 25-4. Biosynthesis of Erythromycin -- Something Extra Bioprospecting: Hunting for Natural Products -- e26. Orbitals and Organic Chemistry: Pericyclic Reactions -- 26-1. Molecular Orbitals of Conjugated Pi Systems -- 26-2. Electrocyclic Reactions -- 26-3. Stereochemistry of Thermal Electrocyclic Reactions -- 26-4. Photochemical Electrocyclic Reactions -- 26-5. Cycloaddition Reactions -- 26-6. Stereochemistry of Cycloadditions -- 26-7. Sigmatropic Rearrangements -- 26-8. Some Examples of Sigmatropic Rearrangements -- 26-9. Summary of Rules for Pericyclic Reactions -- Something Extra Vitamin P. the Sunshine Vitamin -- e27. Synthetic Polymers -- 27-1. Chain-Growth Polymers -- 27-2. Stereochemistry of Polymerization: Ziegler-Natta Catalysts -- 27-3. Copolymers -- 27-4. Step-Growth Polymers -- 27-5. Olefin Metathesis Polymerization -- 27-6. Polymer Structure and Physical Properties -- Biodegradable Polymers -- Appendices -- A. Nomenclature of Polyfunctional Organic Compounds -- B. Acidity Constants for Some Organic Compounds -- C. Glossary -- D. Answers to In-Text Problems.