Essential developmental biology

Summary: "This book presents the basic concepts and facts relating to the developmental biology of animals. It is designed as a core text for undergraduate courses from the first to the fourth year, and also for first year graduate students. It is suitable for both biologically based and medically oriented courses. A basic knowledge of cell and molecular biology is assumed, but no prior knowledge of development, animal structure, or histology should be necessary For this, the fourth edition, the work has two authors. Leslie Dale runs the developmental biology teaching at University College London and has brought his invaluable teaching experience as well as his daily contact with cutting edge research to complement the expertise of the senior author, Jonathan Slack. Two technical advances in particular have been incorporated into the text. The first is single cell transcriptome sequencing which provides a completely new way to observe developmental fate and commitment at a molecular level. The second is CRISPR/Cas9, and other methods for targeted genetic manipulation, that have hugely extended the range of what can be done.