Virus as populations : composition, complexity, quasispecies, dynamics, and biological implications

Summary: 'Virus as Composition, Complexity, Quasispecies, Dynamics, and Biological Implications, Second Edition, explains the fundamental concepts surrounding viruses as complex populations during replication in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, and the probability to be transmitted or respond to treatment all depend on virus population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, and new antiviral strategies are included." -- publisher's website

Record details

ISBN: 9780128163313 (softcover)
ISBN: 0128163313
Physical Description: print
xxi, 404 pages : illustrations, portraits ; 24 cm
Edition: Second edition.
Publisher: London, United Kingdom ; Elsevier/Academic Press, [2020]
Copyright: ©2020

Content descriptions

Bibliography, etc. Note:

Includes bibliographical references and index.

Formatted Contents Note:

Introduction to virus origins and their roles in biological evolution --Molecular basis of genetic variation of viruses: error-prone replication --Darwinian principles acting on highly mutable viruses --Interaction of virus populations with their hosts --Viral fitness as a measure of adaption --Virus population dynamics examined with experimental model systems --Long-term evolution in nature --Quasispecies dynamics in disease prevention and control --Trends in antiviral strategies --Collective population effects in nonviral systems